It doesn’t seem to matter much whether you use a Newtonian or a Cassegrain. That from personal experience and from reading the metadata attached to many images on the web.
What is by far the most important is that the telescope tracks the sky properly. Getting everything mechanically balanced makes the mount’s job much simpler!
Having an autoguider is not essential but certainly makes life immensely easier. Without it you need to have a very well set up and high quality mount and/or take lots of short exposure subs then throw away any which show unacceptable trailing.